Measurement by gas chromatography of urinary hippuric acid and methylhippuric acid as indices of toluene and xylene exposure.
نویسندگان
چکیده
منابع مشابه
Thin-layer chromatography of hippuric and m-methylhippuric acid in urine after mixed exposure to toluene and xylene.
The separation of hippuric and m-methylhippuric acid as toluene and m-xylene metabolites present in urine of people exposed simultaneously to toluene and xylene is described. Chloroform was used for hippuric and m-methylhippuric acid extraction. Satisfactory separation of these metabolites was obtained on TLC plates covered with silica gels and developed in chloroform acetic acid-water (4:1:1);...
متن کاملEvaluation of Toluene Exposure in Workers at Industrial Area of Sidoarjo, Indonesia by Measurement of Urinary Hippuric Acid
Background: Toluene is a harmful substance still being used as a solvent and catalyst in many industries that can increase the level of urinary hippuric acid (UHA). This study was designed to examine the level of toluene and UHA among workers of industrial site in seven companies in Sidoarjo, Indonesia and to analyze the risk factors for abnormal UHA. Methods: This study was an analytical cross...
متن کاملMeasurement of urinary hippuric and m-methylhippuric acids by gas chromatography.
Buchet, J. P., and Lauwerys, R. R. (1973). British Journal ofIndustrial Medicine, 30, 125-128. Measurement of urinary hippuric and m-methylhippuric acids by gas chromatography. A gas chromatographic method for the determination of hippuric and m-methylhippuric acids in urine is described. A known amount of heptadecanoic acid (internal standard) is added to the urine before its extraction with e...
متن کاملUrinary hippuric acid concentration after occupational exposure to toluene.
The results of industrial investigations have shown a correlation between the rate of hippuric acid excretion in a single urine sample collected after daily occupational exposure and the amount of toluene absorbed. The rate of hippuric acid excretion and the average concentration of toluene vapour during exposure time were also related. The quantitative range of the test has been limited to amo...
متن کاملToxicokinetics of toluene and urinary excretion of hippuric acid after human exposure to 2H8-toluene.
Nine male volunteers were exposed to 2H8-toluene (200 mg/m3 for two hours during a workload of 50 W) via inspiratory air with the aid of a breathing valve and mouthpiece. Labelled toluene was used to differentiate between hippuric acid originating from exposure to toluene and hippuric acid normally excreted in urine. The total uptake of toluene was 2.2 (standard deviation (SD) 0.2) mmol, or 50%...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Occupational and Environmental Medicine
سال: 1977
ISSN: 1351-0711
DOI: 10.1136/oem.34.4.305